The tool that’s most associated with the recent progress against malaria is the long-lasting bed net. Bed nets are a fantastic innovation. But we can do even better. We can invent new ways to control the mosquitoes that carry the malaria parasite.

Silicon Valley has some of the smartest engineers and technology business people in the world.

Prohibition is better than no liquor at all.

My view is there’s no bad time to innovate.

The smart thing in the art world is to have one good idea and never have another.

I didn’t want to play it boring and safe. I also didn’t want to innovate too much. Second albums, man, they’re even scarier than first ones.

We, we – as I say, we go in and shake up other industries and I think, you know, we do it differently and I think that industries are not quite the same as a result of Virgin attacking the market.

The way to be successful in the software world is to come up with breakthrough software, and so whether it’s Microsoft Office or Windows, its pushing that forward. New ideas, surprising the marketplace, so good engineering and good business are one in the same.

Any sufficiently advanced technology is indistinguishable from magic.

Those who govern, having much business on their hands, do not generally like to take the trouble of considering and carrying into execution new projects. The best public measures are therefore seldom adopted from previous wisdom, but forced by the occasion.

Polio’s pretty special because once you get an eradication, you no longer have to spend money on it; it’s just there as a gift for the rest of time.

We do not rejoice in victories. We rejoice when a new kind of cotton is grown and when strawberries bloom in Israel.

People expect your behavior to conform to known patterns and conventions. Your task as a strategist is to upset their expectations.

I don’t think that you can invent on behalf of customers unless you’re willing to think long-term, because a lot of invention doesn’t work. If you’re going to invent, it means you’re going to experiment, and if you’re going to experiment, you’re going to fail, and if you’re going to fail, you have to think long term.

Science is magic that works.

I’ve discovered this new electronic technique that creates new speech out of stuff that’s already there.

I think there are going to be a bunch of tablet-like devices. It’s really a different product category.

Genius is always allowed some leeway, once the hammer has been pried from its hands and the blood has been cleaned up.

Really advanced civilization is based on advances in energy.

Imagination decides everything.

We allow no geniuses around our Studio.

Innovation has nothing to do with how many R & D dollars you have. When Apple came up with the Mac, IBM was spending at least 100 times more on R & D. It’s not about money. It’s about the people you have, how you’re led, and how much you get it.

The idea that there is one kind of African is, of course, ridiculous. Sometimes African entrepreneurs want to kill you because you are saying public health is the priority, not roads. Of course they are right to press for that issue, but so are we right, I believe, to argue, for example, that millions of children could and should be vaccinated.

Innovation can only occur where you can breathe free.

The idea that you encourage companies to take their innovative thinkers and think about the most needy – even beyond the market opportunities – that’s something that appropriately ought to be done.

My first phone was two tin cans tied together with string, and it worked pretty good.

To all the musicians who are making reggaeton, let’s put some more effort into it and bring something new to the people!

To turn really interesting ideas and fledgling technologies into a company that can continue to innovate for years, it requires a lot of disciplines.

This is a fantastic time to be entering the business world, because business is going to change more in the next 10 years than it has in the last 50.

I’m interested in things that change the world or that affect the future and wondrous, new technology where you see it, and you’re like, ‚Wow, how did that even happen? How is that possible?‘

We believe that if men have the talent to invent new machines that put men out of work, they have the talent to put those men back to work.

For Africa to move forward, you’ve really got to get rid of malaria.

I think that the idea of having a different approach to every single one of my albums is so exciting to me. I never want to make the same record twice. Why do it? What’s the point?

So I’ve seen life as one long learning process. And if I see – you know, if I fly on somebody else’s airline and find the experience is not a pleasant one, which it wasn’t in – 21 years ago, then I’d think, well, you know, maybe I can create the kind of airline that I’d like to fly on.

For me, when you are have people wondering what is next, what is coming out, you are on the right track.

There’s no point in starting a business unless you’re going to make a dramatic difference to other people’s lives. So if you’ve got an idea that’s gonna make a big difference to other people’s lives, then just get on and do it.

Such a chimerical idea as telegraphing vocal sounds would indeed, to most minds, seem scarcely feasible enough to spend time in working over. I believe, however, that it is feasible and that I have got the cue to the solution of the problem.

If a problem cannot be solved, enlarge it.

Public health service should be as fully organized and as universally incorporated into our governmental system as is public education. The returns are a thousand fold in economic benefits, and infinitely more in reduction of suffering and promotion of human happiness.

Our goal is to make the best devices in the world, not to be the biggest.

Infrastructure web services had to happen.

There is no subject so old that something new cannot be said about it.

It’s OK for China to invent cancer drugs that cure patients in the United States. We want them to catch up. But as the leader, we want to keep setting a very, very high standard. We don’t want them to catch up because we’re slowing down or, even worse, going into reverse.

Of all the inventions of humans, the computer is going to rank near or at the top as history unfolds and we look back. It is the most awesome tool that we have ever invented. I feel incredibly lucky to be at exactly the right place in Silicon Valley, at exactly the right time, historically, where this invention has taken form.

I’m a Silicon Valley guy. I just think people from Silicon Valley can do anything.

Fashion has become so whatever. I don’t think there are any stones left to unturn.

There were people who incorporated melody before me, but I would deem myself the first person to successfully rap and sing.

Innovation distinguishes between a leader and a follower.

The Global Fund is a central player in the progress being achieved on HIV, TB and malaria. It channels resources to help countries fight these diseases. I believe in its impact because I have seen it firsthand.

I am in touch with a company that hopes to replicate my voice. However, they are not replicating my original voice – if they did that, I would sound like a man in his 20s, which would be very strange! They are actually trying to replicate the synthesizer that sits on my wheelchair.

In order for us to have a future that’s exciting and inspiring, it has to be one where we’re a space-bearing civilization.

I have no private interest in the reception of my inventions by the world, having never made, nor proposed to make, the least profit by any of them.

Of the various branches of electrical investigation, perhaps the most interesting and immediately the most promising is that dealing with alternating currents.

I’m always interested in what you can do with technology that people haven’t thought of doing yet.

Without tradition, art is a flock of sheep without a shepherd. Without innovation, it is a corpse.

In the material sciences these are and have been, and are most surely likely to continue to be heroic days.

Before I do anything, I think, well what hasn’t been seen. Sometimes, that turns out to be something ghastly and not fit for society. And sometimes that inspiration becomes something that’s really worthwhile.

To raise new questions, new possibilities, to regard old problems from a new angle, requires creative imagination and marks real advance in science.

Towering genius disdains a beaten path. It seeks regions hitherto unexplored.

You cannot make a giant space company in your dorm room. Not today. And the reason is that the heavy lifting infrastructure isn’t in place.

I’m never going to go to Mars, but I’ve helped inspire, thank goodness, the people who built the rockets and sent our photographic equipment off to Mars.